99% Pharma Grade Isotretinoin Vitamin a Acid 4759-48-2 for
Treatment of Acne Embolism
- Name: Isotretinoin
- Model NO.: 4759-48-2
- Customized: Non-Customized
- Suitable for: Elderly, Children, Adult
- Purity: >99%
- Synonyms: Accutane;Isoretinoin
- Mf: C20h28o2
- Einecs: 225-296-0
- Delivery: Sent out Within 12 Hours
- Transport Package: Foil Bag
- Origin: China
- Powder: Yes
- Certification: GMP, HSE, ISO 9001, USP, BP
- State: Solid
- CAS: 4759-48-2
- MW: 300.44
- Chemical Properties: Yellow-Orange Crystalline Powder
- Specification: ISO9001
- HS Code: 2942000000
Isotretinoin also known as 13-cis-retinoic acid, is an oral
pharmaceutical drug primarily used to treat severe nodular acne.
Rarely, it is also used to prevent certain skin cancers
(squamous-cell carcinoma), and in the treatment of other cancers.
It is used to treat harlequin-type ichthyosis, a usually lethal
skin disease, and lamellar ichthyosis. It is a retinoid, meaning it
is related to vitamin A, and is found in small quantities naturally
in the body. Its isomer, tretinoin, is also an acne drug.
|Production date||2016/07/21||Shelf life||2018/07.20|
|Test Items||Specification||Test Results|
|Appearance||Yellow or orange crystalline powder||Complies|
|Loss on drying||Not more than 0.5%||0.02%|
|Residue on ignition||Not more than 0.1%||0.02%|
|Heavy metals||Not more than 0.002%||Less than 0.002%|
|Tretinoin||Not more than 1.0%||0.1%|
|Assay||98.0%~102.0 %( Calculated on the dried basis)||99.8%|
|Conclusion||this product conforms to USP34|
Isotretinoin is primarily used as a treatment for severe acne. The
most common adverse effects are a transient worsening of acne
(lasting 2–3 weeks), dry lips (cheilitis), dry and fragile skin,
and an increased susceptibility to sunburn. Uncommon and rare side
effects include muscle aches and pains (myalgias), and headaches.
Isotretinoin is known to cause birth defects due to in utero
exposure because of the molecule's close resemblance to retinoic
acid, a natural vitamin A derivative which controls normal
Isotretinoin is a form of vitamin A. It reduces the amount of oil
released by oil glands in your skin, and helps your skin renew
itself more quickly.
Isotretinoin is used to treat severe nodular acne that has not
responded to other treatments, including antibiotics.
How to Use Isotretinoin
Read the Medication Guide provided by your pharmacist before you
start using isotretinoin and each time you get a refill. Read and
sign a Patient Information/Informed Consent form before you start
taking this medication. If you have any questions about
isotretinoin, consult your doctor or pharmacist before taking the
Swallow capsules whole. Do not crush or chew them. Isotretinoin is
usually taken twice daily for 15-20 weeks, or as directed by your
doctor. Directions for most generic forms of isotretinoin state
that it should be taken with meals. However, the FDA has indicated
that the Absorica brand may be taken with or without food. Food
helps increase absorption of this drug into your bloodstream. Ask
your doctor or pharmacist for more information. Take this drug with
a full glass of water, and do not lie down for 10 minutes after
The dosage is based on your medical condition, weight, and response
Your acne may worsen during the first few days of taking this drug,
and it may take up to 1-2 months before you notice the full benefit
of this medication. If severe acne returns, a second course of
treatment may be started after you have stopped taking the drug for
2 months. The manufacturer does not recommend long-term use of
isotretinoin. Do not take more than the recommended dose.
Since this drug can be absorbed through the skin and lungs and may
harm an unborn baby, women who are pregnant or who may become
pregnant should not handle this medication or breathe the dust from
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The MOQ is 10 grams for all.FOB depends on your quantity.
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